Investigating the causal relationship between ankylosing spondylitis and osteoporosis in the European population: a bidirectional Mendelian randomization study

BackgroundAnkylosing Spondylitis (AS) is an inflammatory condition affecting the spine, which may lead to complications such as osteoporosis (OP). Many observational studies have demonstrated a close relationship with strong evidence between OP and AS. The combination of AS and OP is already an indi...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Jian Mei, Hongxin Hu, Haiqi Ding, Ying Huang, Wenming Zhang, Xiaoqing Chen, Xinyu Fang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	Mendelian randomization ankylosing spondylitis osteoporosis bone mineral density single nucleotide polymorphisms GWAS
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163258/full