Ceramides in peripheral arterial plaque lead to endothelial cell dysfunction

Background: Peripheral arterial atheroprogression is increasingly prevalent, and is a risk factor for major limb amputations in individuals with risk factors such as diabetes. We previously demonstrated that bioactive lipids are significantly altered in arterial tissue of individuals with diabetes a...

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Bibliographic Details

Published in:	JVS - Vascular Science
Main Authors:	Rodrigo Meade, BS, Yang Chao, MD, PhD, Nikolai Harroun, MD, Chenglong Li, MD, Shahab Hafezi, MD, Fong-Fu Hsu, PhD, Clay F. Semenkovich, MD, Mohamed A. Zayed, MD, PhD, MBA
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Subjects:	Ceramide Diabetes Endothelial dysfunction Peripheral arterial disease Sphingolipid Sphingomyelinase
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666350323000858