IL-40 is up-regulated in the synovial fluid and cartilage of osteoarthritis patients and contributes to the alteration of chondrocytes phenotype in vitro

Abstract Introduction IL-40 is a novel cytokine associated with autoimmune connective tissue disorders such as rheumatoid arthritis (RA) or Sjögren syndrome. We have previously shown an accumulation of IL-40 in the RA joint and its expression by immune cells and fibroblasts. Therefore, we aimed to a...

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Bibliographic Details

Published in:	Arthritis Research & Therapy
Main Authors:	L. Andrés Cerezo, A. Navrátilová, M. Kuklová, A. Prokopcová, J. Baloun, T. Kropáčková, D. Veigl, S. Popelka, P. Fulín, R. Ballay, K. Pavelka, J. Vencovský, L. Šenolt
Format:	Article
Language:	English
Published:	BMC 2024-07-01
Subjects:	Interleukin 40 Osteoarthritis Cartilage Chondrocytes
Online Access:	https://doi.org/10.1186/s13075-024-03372-z