Preparation of RGD-modified liposomes encapsulated with shikonin and its targeted anti-melanoma effects

Melanoma is the most aggressive skin tumor, and conventional treatment is ineffective. Studies have shown that shikonin, derived from the traditional Chinese medicine Lithospermum erythrorhizon, has various anticancer activities. In this work, RGD- modified liposomes encapsulated with shikonin (RGD-...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Hao Zhang, Ying Zhao, Tingting Chen, Xinliang Mao, Jiping Li, Li Fan, Min Li, Xianchun Wen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	shikonin melanoma liposomes RGD αVβ3 integrin
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1573628/full