CDDO-Me Attenuates Astroglial Autophagy via Nrf2-, ERK1/2-SP1- and Src-CK2-PTEN-PI3K/AKT-Mediated Signaling Pathways in the Hippocampus of Chronic Epilepsy Rats

Clasmatodendrosis is an autophagic astroglial death showing extensive swollen cell bodies with vacuoles and disintegrated/beaded processes. This astroglial degeneration is closely relevant to the synchronous epileptiform discharges. However, the underlying molecular mechanisms and the roles of clasm...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Ji-Eun Kim, Tae-Cheon Kang
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Subjects:	astrocyte Bif-1 clasmatodendrosis GSK3β HSP25 seizure
Online Access:	https://www.mdpi.com/2076-3921/10/5/655