Enhanced penetration and biofilm eradication by sophorolipid micelles encapsulating Honokiol: a comprehensive solution for biofilm-associated lung infections

Abstract Background Biofilm-associated lung infections, particularly those caused by Staphylococcus aureus (S. aureus), pose significant clinical challenges to conventional therapies. S. aureus Biofilm infections are refractory to treatment due to the presence of persister bacterial cells and the ba...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Shiyu Lin, Xiaojuan Li, Wei Zhang, Gang Shu, Tim Tolker-Nielsen, Haohuan Li, Funeng Xu, Juchun Lin, Guangneng Peng, Li Zhang, Hualin Fu
Format:	Article
Language:	English
Published:	BMC 2025-02-01
Subjects:	Staphylococcus aureus biofilm Sophorolipid Honokiol Nanomicelle
Online Access:	https://doi.org/10.1186/s12951-025-03144-0