HLA, gut microbiome and hepatic autoimmunity

Genetic susceptibility to autoimmune liver diseases is conferred mainly by polymorphisms of genes encoding for the human leukocyte antigens (HLA). The strongest predisposition to autoimmune hepatitis type 1 (AIH-1) is linked to the allele DRB1*03:01, possession of which is associated with earlier di...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Benedetta Terziroli Beretta-Piccoli, Giorgina Mieli-Vergani, Diego Vergani
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Subjects:
autoimmune hepatitis
AIH
primary biliary cholangitis (PBC)
primary sclerosing cholangites (PSC)
gut microbiome
human leucocyte antigen (HLA)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.980768/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.980768/full

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