Multi-dimensional characterization of immunological profiles in small cell lung cancer uncovers clinically relevant immune subtypes with distinct prognoses and therapeutic vulnerabilities

Small-cell lung cancer (SCLC) is generally considered a 'homogenous' disease, with little documented inter-tumor heterogeneity in treatment guidance or prognosis evaluation. The precise identification of clinically relevant molecular subtypes remains incomplete and their translation into c...

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Bibliographic Details

Published in:	Pharmacological Research
Main Authors:	Lin Yang, Zicheng Zhang, Jiyan Dong, Yibo Zhang, Zijian Yang, Yiying Guo, Xujie Sun, Junling Li, Puyuan Xing, Jianming Ying, Meng Zhou
Format:	Article
Language:	English
Published:	Elsevier 2023-08-01
Subjects:	Digital spatial profiling Immune subtypes Small cell lung cancer Tumor microenvironment Formalin-fixed-paraffin-embedded
Online Access:	http://www.sciencedirect.com/science/article/pii/S1043661823002001