Molecular interactions, structural effects, and binding affinities between silver ions (Ag+) and amyloid beta (Aβ) peptides

Abstract Because silver is toxic to microbes, but not considered toxic to humans, the metal has been used as an antimicrobial agent since ancient times. Today, silver nanoparticles and colloidal silver are used for antibacterial purposes, and silver-peptide and similar complexes are being developed...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Amanda L. Lakela, Elina Berntsson, Faraz Vosough, Jüri Jarvet, Suman Paul, Andreas Barth, Astrid Gräslund, Per M. Roos, Sebastian K. T. S. Wärmländer
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-02-01
Subjects:	Alzheimer’s disease Amyloid aggregation Metal-protein binding Neurodegeneration Metal toxicity Spectroscopy
Online Access:	https://doi.org/10.1038/s41598-024-59826-6