Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV.

Establishment of viral latency is not only essential for lifelong Kaposi's sarcoma-associated herpesvirus (KSHV) infection, but it is also a prerequisite of viral tumorigenesis. The latent viral DNA has a complex chromatin structure, which is established in a stepwise manner regulated by host e...

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Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Nenavath Gopal Naik, Thomas Hong Nguyen, Lauren Roberts, Luke Todd Fischer, Katherine Glickman, Gavin Golas, Bernadett Papp, Zsolt Toth
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2020-01-01
Online Access:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008268&type=printable