Dexamethasone Attenuates Oncostatin M Production via Suppressing of PI3K/Akt/NF-κB Signaling in Neutrophil-like Differentiated HL-60 Cells

Oncostatin M (OSM) plays a role in various inflammatory reactions, and neutrophils are the main source of OSM in pulmonary diseases. However, there is no evidence showing the mechanism of OSM production in neutrophils. While dexamethasone (Dex) has been known to exert anti-inflammatory activity in v...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Na-Ra Han, Seong-Gyu Ko, Hi-Joon Park, Phil-Dong Moon
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Subjects:	oncostatin M dexamethasone neutrophil-like differentiated HL-60 cells PI3K Akt NF-κB
Online Access:	https://www.mdpi.com/1420-3049/27/1/129