Inhibition of COX-2 signaling favors E. coli during urinary tract infection

Abstract Background To avoid the overuse of antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), acting via cyclooxygenase (COX) inhibition, have been used to reduce pain and as an alternative treatment for uncomplicated urinary tract infections (UTIs). However, clinical studies evaluating N...

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Bibliographic Details
Published in:Journal of Inflammation
Main Authors: Soumitra Mohanty, Ciska Lindelauf, John Kerr White, Andrea Scheffschick, Ewa Ehrenborg, Isak Demirel, Hanna Brauner, Annelie Brauner
Format: Article
Language:English
Published: BMC 2023-09-01
Subjects:
E. coli
COX-2
Antimicrobial peptide
Cytokines
Urinary tract infection
Online Access:https://doi.org/10.1186/s12950-023-00356-9

Internet

https://doi.org/10.1186/s12950-023-00356-9

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