Preparation and characterisation of Dextran-70 hydrogel for controlled release of praziquantel

A hydrogel was developed from 70 kDa dextran (DEX-70) and praziquantel (PZQ) incorporated as a model drug. Biopharmaceutical properties, such as solubility and dissolution rate, were analysed in the design of the hydrogel. Furthermore, the hydrogel was also characterized by IR spectroscopy and DSC....

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Bibliographic Details
Published in:Brazilian Journal of Pharmaceutical Sciences
Main Authors: Flávio dos Santos Campos, Douglas Lopes Cassimiro, Marisa Spirandeli Crespi, Adélia Emília Almeida, Maria Palmira Daflon Gremião
Format: Article
Language:English
Published: Universidade de São Paulo 2013-03-01
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000100009