Transcription factor ELF-1 protects against colitis by maintaining intestinal epithelium homeostasis

Abstract Inflammatory bowel disease (IBD) is a chronic, relapsing, and remitting disease characterized by chronic inflammation in the gastrointestinal tract. The exact etiology and pathogenesis of IBD remain elusive. Although ELF-1 has been known to be highly expressed in epithelial cells for past t...

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Bibliographic Details
Published in:Communications Biology
Main Authors: Gege He, Pingping Liu, Xiaoyan Xuan, Min Zhang, Hongxia Zhang, Ka Yang, Yusheng Luan, Qian Yang, Jingyuan Yang, Qianru Li, Huaixin Zheng, Peng Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Online Access:https://doi.org/10.1038/s42003-025-07742-4