Metabolic dysfunction-associated steatotic liver disease attenuates the predictive value of the triglyceride–glucose index for carotid plaque: evidence of insulin resistance-independent pathways

BackgroundInsulin resistance (IR), a key driver of atherosclerosis, is associated with cardiovascular risks such as carotid plaque formation. While the triglyceride–glucose (TyG) index has been established as a reliable surrogate marker of IR, its association with carotid plaque formation in individ...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Fang Zhang, Zheng Wang, Han Zhang, Yu-Qiang Zuo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	TyG index insulin resistance MASLD carotid plaque effect modification
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1696652/full