Thiopurine S-methyltransferase polymorphisms in acute lymphoblastic leukemia, inflammatory bowel disease and autoimmune disorders: influence on treatment response

Rachid Abaji,1 Maja Krajinovic2 1Department of Pharmacology, 2Departments of Pediatrics and Pharmacology, CHU Sainte-Justine Research Center, University of Montreal, Montreal, QC, Canada Abstract: The thiopurine S-methyltransferase (TPMT) gene encodes for the TPMT enzyme that plays a crucial role in...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Pharmacogenomics and Personalized Medicine
المؤلفون الرئيسيون: Abaji R, Krajinovic M
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Dove Medical Press 2017-05-01
الموضوعات:
الوصول للمادة أونلاين:https://www.dovepress.com/thiopurine-s-methyltransferase-polymorphisms-in-acute-lymphoblastic-le-peer-reviewed-article-PGPM