Macranthoidin B restrains the epithelial-mesenchymal transition through COX-2/PGE2 pathway in endometriosis

IntroductionMacranthoidin B is one of the primary and unique triterpenoid saponin metabolites from Lonicera macranthoides Hand. –Mazz, which is used to treat endometriosis (EMS) in traditional Chinese medicine. However, the effect of macranthoidin B remains unknown in EMS. This study aimed to elucid...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Yi Ding, Xiaoqian Yang, Qinghua Wei, Xuanming Bi, Yuxin Zhang, Yuxia Ma, Meisen Yang, Xiaoyu Xu, Cong Li, Qin Wang, Yi Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-12-01
Subjects:	macranthoidin B endometriosis COX-2/PGE2 pathway epithelial-mesenchymal transition invasion and metastasis
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1492098/full