Investigating the anti-filarial efficacy and molecular interactions of thiadiazol derivative: Insight from quantum chemical calculations, pharmacokinetics, and molecular docking studies

Parasitic infections such as lymphatic filariasis (elephantiasis) solely result from the infestation of a slender and thread-like worm. This condition precipitates swelling, often accompanied by skin alterations, potentially leading to substantial disability and disfigurement. Recent advancements in...

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Bibliographic Details

Published in:	Chemical Physics Impact
Main Authors:	Eze A. Adindu, Bassey O. Ekpong, Musa Runde, Aondoungwa M. Atotse, Folasade O. Ojumola, Alpha O. Gulack, Aniekan E. Owen, Solomon O. Iyam, Michael O. Odey, Innocent Benjamin, Terkumbur E. Gber, Hitler Louis
Format:	Article
Language:	English
Published:	Elsevier 2024-06-01
Subjects:	Thiadiazol derivative DFT Molecular docking Admet Lymphatic filariasis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667022424000033