TET1 facilitates specification of early human lineages including germ cells

Summary: Ten Eleven Translocation 1 (TET1) is a regulator of localized DNA demethylation through the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). To examine DNA demethylation in human primordial germ cell-like cells (hPGCLCs) induced from human embryonic stem cells (hESCs)...

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書誌詳細

出版年:	iScience
主要な著者:	Fei-Man Hsu, Qiu Ya Wu, Emily B. Fabyanic, Alex Wei, Hao Wu, Amander T. Clark
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2023-07-01
主題:	Epigenetics Developmental biology Embryology
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2589004223012683