The RNA-Binding Landscape of HAX1 Protein Indicates Its Involvement in Translation and Ribosome Assembly

HAX1 is a human protein with no known homologues or structural domains. Mutations in the <i>HAX1</i> gene cause severe congenital neutropenia through mechanisms that are poorly understood. Previous studies reported the RNA-binding capacity of HAX1, but the role of this binding in physiol...

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發表在:	Cells
Main Authors:	Anna Balcerak, Ewelina Macech-Klicka, Maciej Wakula, Rafal Tomecki, Krzysztof Goryca, Malgorzata Rydzanicz, Mateusz Chmielarczyk, Malgorzata Szostakowska-Rodzos, Marta Wisniewska, Filip Lyczek, Aleksandra Helwak, David Tollervey, Grzegorz Kudla, Ewa A. Grzybowska
格式:	Article
語言:	英语
出版:	MDPI AG 2022-09-01
主題:	RNA–protein binding HAX1 RIP-seq CRAC translation ribosome assembly
在線閱讀:	https://www.mdpi.com/2073-4409/11/19/2943