Preclinical Study of Pain Neuropeptide Expression in Murine Sensory Neurons Induced by Irradiated Osteoclasts in the Context of Stereotactic Body Radiation Therapy

Stereotactic body radiation therapy (SBRT) for lung tumors near the chest wall often causes significant chest wall pain (CWP), negatively impacting patients’ quality of life. The mechanisms behind SBRT-induced CWP remain unclear and may involve multiple factors. We investigated crosstalk between rad...

Full description

Bibliographic Details

Published in:	Cells
Main Authors:	Sun H. Park, Megan Peters, Caleb Aguayo, Michael K. Farris, Ryan T. Hughes, Joseph Moore, Michael T. Munley, Kaitlyn E. Reno, Jeffrey A. Foster, Jean Gardin, George W. Schaaf, J. Mark Cline, Christopher M. Peters, Jeffrey S. Willey
Format:	Article
Language:	English
Published:	MDPI AG 2025-08-01
Subjects:	stereotactic body radiation therapy chest wall pain osteoclasts sensory neurons bisphosphonates neuropeptides
Online Access:	https://www.mdpi.com/2073-4409/14/17/1324