drexml: A command line tool and Python package for drug repurposing

We introduce drexml, a command line tool and Python package for rational data-driven drug repurposing. The package employs machine learning and mechanistic signal transduction modeling to identify drug targets capable of regulating a particular disease. In addition, it employs explainability tools t...

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Bibliographic Details
Published in:Computational and Structural Biotechnology Journal
Main Authors: Marina Esteban-Medina, Víctor Manuel de la Oliva Roque, Sara Herráiz-Gil, María Peña-Chilet, Joaquín Dopazo, Carlos Loucera
Format: Article
Language:English
Published: Elsevier 2024-12-01
Subjects:
Explainable machine learning
Drug repurposing
Omics
Mechanistic models
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024000515

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http://www.sciencedirect.com/science/article/pii/S2001037024000515

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