drexml: A command line tool and Python package for drug repurposing

We introduce drexml, a command line tool and Python package for rational data-driven drug repurposing. The package employs machine learning and mechanistic signal transduction modeling to identify drug targets capable of regulating a particular disease. In addition, it employs explainability tools t...

書誌詳細
出版年:	Computational and Structural Biotechnology Journal
主要な著者:	Marina Esteban-Medina, Víctor Manuel de la Oliva Roque, Sara Herráiz-Gil, María Peña-Chilet, Joaquín Dopazo, Carlos Loucera
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2024-12-01
主題:	Explainable machine learning Drug repurposing Omics Mechanistic models
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2001037024000515

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