A Validated Model to Predict Severe Weight Loss in Amyotrophic Lateral Sclerosis

ABSTRACT Severe weight loss in amyotrophic lateral sclerosis (ALS) is common, multifactorial, and associated with shortened survival. Using longitudinal weight data from over 6000 patients with ALS across three cohorts, we built an accelerated failure time model to predict the risk of future severe...

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Bibliographic Details

Published in:	Annals of Clinical and Translational Neurology
Main Authors:	David G. Lester, Kevin Talbot, Martin R. Turner, Alexander G. Thompson, the Pooled Resource Open‐Access ALS Clinical Trials Consortium
Format:	Article
Language:	English
Published:	Wiley 2025-09-01
Subjects:	amyotrophic lateral sclerosis clinical prediction model motor neuron disease nutrition weight loss
Online Access:	https://doi.org/10.1002/acn3.70129