Optimization of simvastatin transdermal patch for hyperlipidemia treatment in rat model

Abstract Objective Biopharmaceutics Classification System says that simvastatin (SMV) is a Class II drug with low bioavailability (5%). This is because it dissolves slowly and is broken down a lot in the first pass. Simvastatin transdermal patches were produced as part of this study's aim to tr...

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Bibliographic Details
Published in:Future Journal of Pharmaceutical Sciences
Main Authors: Neetu, Anubhav Anand, Dharamveer Panjwani
Format: Article
Language:English
Published: SpringerOpen 2024-02-01
Subjects:
Transdermal patch
Simvastatin
Permeation enhancer
Box Behnken
Antihyperlipidemic
Online Access:https://doi.org/10.1186/s43094-024-00606-4

Internet

https://doi.org/10.1186/s43094-024-00606-4

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