Human dendritic cells sequentially matured with CD4+ T cells as a secondary signal favor CTL and long-term T memory cell responses

Dendritic cells (DCs) are professional antigen-presenting cells involved in the control and initiation of immune responses. In vivo, DCs exposed at the periphery to maturation stimuli migrate to lymph nodes, where they receive secondary signals from CD4+ T helper cells. These DCs become able to init...

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Bibliographic Details
Published in:Biological Research
Main Authors: Thomas Simon, Séverine Tanguy-Royer, Pierre-Joseph Royer, Nicolas Boisgerault, Jihane Frikeche, Jean-François Fonteneau, Marc Grégoire
Format: Article
Language:English
Published: BMC 2012-01-01
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000100005