Metabolomic characterisation of the glioblastoma invasive margin reveals a region-specific signature

Isocitrate dehydrogenase wild-type glioblastoma (GBM) is characterised by a heterogeneous genetic landscape resulting from dynamic competition between tumour subclones to survive selective pressures. Improvements in metabolite identification and metabolome coverage have led to increased interest in...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	James Wood, Stuart J. Smith, Marcos Castellanos-Uribe, Anbarasu Lourdusamy, Sean T. May, David A. Barrett, Richard G. Grundy, Dong-Hyun Kim, Ruman Rahman
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Subjects:	Glioblastoma Metabolomics Invasive margin Liquid-chromatography mass spectrometry
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024173409