Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle

Abstract Background Human-to-human transmission of symbiotic, anaerobic bacteria is a fundamental evolutionary adaptation essential for membership of the human gut microbiota. However, despite its importance, the genomic and biological adaptations underpinning symbiont transmission remain poorly und...

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Bibliographic Details

Published in:	Genome Biology
Main Authors:	Hilary P. Browne, Alexandre Almeida, Nitin Kumar, Kevin Vervier, Anne T. Adoum, Elisa Viciani, Nicholas J. R. Dawson, Samuel C. Forster, Claire Cormie, David Goulding, Trevor D. Lawley
Format:	Article
Language:	English
Published:	BMC 2021-08-01
Subjects:	Sporulation Intestinal microbiota Microbiome Metagenomics Host adaptation Genome reduction
Online Access:	https://doi.org/10.1186/s13059-021-02428-6