Reduced anticoagulation targets in extracorporeal life support (RATE): protocol for a pre-planned secondary Bayesian analysis of the rate trial

Abstract Background The RATE trial is a three-arm non-inferiority randomized controlled trial in adult patients treated with extracorporeal membrane oxygenation (ECMO) on the effect of anticoagulation levels on mortality, hemorrhagic, and thrombotic complications. The current protocol presents the r...

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Bibliographic Details

Published in:	Trials
Main Authors:	Olivier van Minnen, Maximilian Linde, Annemieke Oude Lansink-Hartgring, Bas van den Boogaard, Jeroen J. H. Bunge, Thijs S. R. Delnoij, Carlos V. Elzo Kraemer, Marijn Kuijpers, Jacinta J. Maas, Jesse de Metz, Marcel van de Poll, Dinis dos Reis Miranda, Alexander P. J. Vlaar, Don van Ravenzwaaij, Walter M. van den Bergh
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Online Access:	https://doi.org/10.1186/s13063-025-08737-6