Immune cell proportions correlate with clinicogenomic features and ex vivo drug responses in acute myeloid leukemia

IntroductionThe implementation of small-molecule and immunotherapies in acute myeloid leukemia (AML) has been challenging due to genetic and epigenetic variability amongst patients. There are many potential mechanisms by which immune cells could influence small-molecule or immunotherapy responses, y...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Kyle A. Romine, Daniel Bottomly, William Yashar, Nicola Long, Matthew Viehdorfer, Shannon K. McWeeney, Jeffrey W. Tyner
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	AML – acute myeloid leukemia immune therapeutics checkpoint inhibition therapy RNAseq analysis functional genomic data
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1192829/full