<i>IKZF1</i> Alterations and Therapeutic Targeting in B-Cell Acute Lymphoblastic Leukemia

<i>IKZF1</i> encodes the transcription factor IKAROS, a zinc finger DNA-binding protein with a key role in lymphoid lineage development. IKAROS plays a critical role in the development of lineage-restricted mature lymphocytes. Deletions within <i>IKZF1</i> in B-cell acute lym...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Jonathan Paolino, Harrison K. Tsai, Marian H. Harris, Yana Pikman
Format:	Article
Language:	English
Published:	MDPI AG 2024-01-01
Subjects:	<i>IKZF1</i> IKAROS B-cell acute lymphoblastic leukemia
Online Access:	https://www.mdpi.com/2227-9059/12/1/89