Case Report: Efficacy, safety, and favorable long-term outcome of early treatment with IL-1 inhibitors in a patient with chronic infantile neurological cutaneous articular (CINCA) syndrome caused by NLRP3 mosaicism

Chronic infantile neurological cutaneous articular (CINCA) syndrome is an autoinflammatory disease encompassed in the group of cryopyrin-associated periodic syndromes (CAPS). Patients suffering from CINCA have an elevated risk of developing chronic sequelae, including deforming arthropathy, chronic...

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Bibliographic Details

Published in:	Frontiers in Pediatrics
Main Authors:	Giorgio Costagliola, Sofia D’Elios, Susanna Cappelli, Francesco Massei, Giulia Maestrini, Alessandra Beni, Diego Peroni, Rita Consolini
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Subjects:	anakinra autoinflammatory disorders canakinumab chronic infantile neurological cutaneous articular syndrome cryopyrin-associated syndromes (CAPS) inflammasome
Online Access:	https://www.frontiersin.org/articles/10.3389/fped.2024.1379616/full