Study of the Correlation of EGFR and K-RAS Gene Mutations with Its Protein Expression in Non-small Cell Lung Cancer

OBJECTIVE To investigate gene mutations of epidermal growth factor receptor (EGFR) and K-RAS (Kirsten rat sarcoma viral oncogene) in Chinese patients with non-small cell lung cancer (NSCLC), and study the correlation with its protein expression and its clinical signifi cance on gefinib. METHODS...

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Bibliographic Details

Published in:	Cancer Biology & Medicine
Main Authors:	Huan-ling LUAN, Lei-na SUN, Na DONG
Format:	Article
Language:	English
Published:	China Anti-Cancer Association 2010-04-01
Subjects:	Epidermal growth factor receptor (EGFR) Kirsten rat sarcoma viral oncogene (K-RAS) Non-small cell lung cancer (NSCLC) EGFR tyrosine kinase inhibitor (EGFR-TKI).
Online Access:	http://www.cancerbiomed.org/index.php/cocr/article/view/138