Leishmania infantum exploits the anti-ferroptosis effects of Nrf2 to escape cell death in macrophages

Summary: Macrophages are major host cells for the protozoan Leishmania parasite. Depending on their activation state, they either contribute to the detection and elimination of Leishmania spp. or promote parasite resilience. Here, we report that the activation of the transcription factor nuclear fac...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Clément Blot, Mathilde Lavernhe, Geanncarlo Lugo-Villarino, Kimberley Coulson, Marie Salon, Margot Tertrais, Rémi Planès, Karin Santoni, Hélène Authier, Godefroy Jacquemin, Mouna Rahabi, Mélissa Parny, Isabelle Raymond Letron, Etienne Meunier, Lise Lefèvre, Agnès Coste
Format:	Article
Language:	English
Published:	Elsevier 2024-09-01
Subjects:	CP: Immunology CP: Microbiology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124724010714