The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer.

High macrophage infiltration has been correlated to improved survival in colorectal cancer (CRC). Tumor associated macrophages (TAMs) play complex roles in tumorigenesis since they are believed to hold both tumor preventing (M1 macrophages) and tumor promoting (M2 macrophages) activities. Here we ha...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Sofia Edin, Maria L Wikberg, Anna M Dahlin, Jörgen Rutegård, Åke Öberg, Per-Arne Oldenborg, Richard Palmqvist
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23077543/pdf/?tool=EBI