1-Piperidine Propionic Acid as an Allosteric Inhibitor of Protease Activated Receptor-2

In the last decades, studies on the inflammatory signaling pathways in multiple pathological contexts have revealed new targets for novel therapies. Among the family of G-protein-coupled Proteases Activated Receptors, PAR2 was identified as a driver of the inflammatory cascade in many pathologies, r...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Monica Chinellato, Matteo Gasparotto, Santina Quarta, Mariagrazia Ruvoletto, Alessandra Biasiolo, Francesco Filippini, Luca Spiezia, Laura Cendron, Patrizia Pontisso
Format:	Article
Language:	English
Published:	MDPI AG 2023-10-01
Subjects:	G protein-coupled receptors Protease Activated Receptor 2 allosteric modulator 1-piperidinepropionic acid molecular dynamics
Online Access:	https://www.mdpi.com/1424-8247/16/10/1486