Altered Immunomodulatory Responses in the CX3CL1/CX3CR1 Axis Mediated by hMSCs in an Early In Vitro SOD1^G93A Model of ALS

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron (MN) disease characterized by progressive MN loss and muscular atrophy resulting in rapidly progressive paralysis and respiratory failure. Human mesenchymal stem/stromal cell (hMSC)-based therapy has been suggested to prolong MN survival vi...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Anastasia Sarikidi, Ekaterini Kefalakes, Christine S. Falk, Ruth Esser, Arnold Ganser, Nadine Thau-Habermann, Susanne Petri
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	amyotrophic lateral sclerosis SOD1<sup>G93A</sup> motor neurons human mesenchymal stem/stromal cells fractalkine
Online Access:	https://www.mdpi.com/2227-9059/10/11/2916