Oral treatment with the all-d-peptide RD2 enhances cognition in aged beagle dogs – A model of sporadic Alzheimer’s disease

Disease-modifying therapies to treat Alzheimer's disease (AD) are of fundamental interest for aging humans, societies, and health care systems. Predictable disease progression in transgenic AD models favors preclinical studies employing a preventive study design with an early pre-symptomatic tr...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Heliyon
المؤلفون الرئيسيون:	Janine Kutzsche, Sarah Schemmert, Tuyen Bujnicki, Christian Zafiu, Steffen Halbgebauer, Victoria Kraemer-Schulien, Marlene Pils, Lara Blömeke, Julia Post, Andreas Kulawik, Dagmar Jürgens, Wolfgang M. Rossberg, Michael Hümpel, Oliver Bannach, Markus Otto, Joseph A. Araujo, Antje Willuweit, Dieter Willbold
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2023-08-01
الموضوعات:	Alzheimer's disease Aβ oligomers Tau oligomers Cognitively impaired aged Beagle dogs Sporadic AD animal model Disease-modifying therapy
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2405844023056517