Withaferin A as a Potential Therapeutic Target for the Treatment of Angiotensin II-Induced Cardiac Cachexia

In our previous studies, we showed that the generation of ovarian tumors in NSG mice (immune-compromised) resulted in the induction of muscle and cardiac cachexia, and treatment with withaferin A (WFA; a steroidal lactone) attenuated both muscle and cardiac cachexia. However, our studies could not a...

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Bibliographic Details

Published in:	Cells
Main Authors:	Vasa Vemuri, Nicholas Kratholm, Darini Nagarajan, Dakotah Cathey, Ahmed Abdelbaset-Ismail, Yi Tan, Alex Straughn, Lu Cai, Jiapeng Huang, Sham S. Kakar
Format:	Article
Language:	English
Published:	MDPI AG 2024-05-01
Subjects:	cardiac cachexia cardiac disorders cardiac dysfunction withaferin A angiotensin II inflammatory cytokines
Online Access:	https://www.mdpi.com/2073-4409/13/9/783