Eplerenone, diabetes, and chronic kidney disease in patients hospitalized for acute heart failure: findings from the EARLIER trial

Abstract Background Mineralocorticoid receptor antagonists (MRAs) are often underutilized in patients with heart failure (HF), particularly those with diabetes and/or chronic kidney disease (CKD). However, the impact of concurrent diabetes and CKD on the efficacy and safety of eplerenone in acute HF...

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Bibliographic Details

Published in:	Cardiovascular Diabetology
Main Authors:	Masatake Kobayashi, Akira Yamashina, Kazuhiro Satomi, Masataka Watanabe, Ryu Takagi, Ayako Tezuka, Shin Ito, Masanori Asakura, Masafumi Kitakaze
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Subjects:	Acute heart failure Eplerenone Mineralocorticoid receptor antagonist Diabetes Chronic kidney disease Prognosis
Online Access:	https://doi.org/10.1186/s12933-025-02659-y