Primary Human Blood Dendritic Cells for Cancer Immunotherapy—Tailoring the Immune Response by Dendritic Cell Maturation

Dendritic cell (DC)-based cancer vaccines hold the great promise of tipping the balance from tolerance of the tumor to rejection. In the last two decades, we have gained tremendous knowledge about DC-based cancer vaccines. The maturation of DCs has proven indispensable to induce immunogenic T cell r...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Simone P. Sittig, I. Jolanda M. de Vries, Gerty Schreibelt
Format:	Article
Language:	English
Published:	MDPI AG 2015-12-01
Subjects:	human blood DC (dendritic cell) subsets maturation DC-based cancer vaccines plasmacytoid DC myeloid DC CD141+ myeloid DC (mDC) CD1c+ mDC
Online Access:	http://www.mdpi.com/2227-9059/3/4/282