Reclassification of BRCA1 and BRCA2 Variants of Unknown Significance in a Turkish Cohort; A Single-Center, Retrospective Study

Objective: Accurate classification of breast cancer susceptibility gene (BRCA)1/2 variants is important to delineate candidates for surgical or medical treatment. We retrospectively analyzed BRCA1/BRCA2 sequencing data and reclassified the BRCA1/2 variants of unknown significance (VUS) in Turkish pa...

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Bibliographic Details

Published in:	European Journal of Breast Health
Main Authors:	Leyla Özer, Süleyman Aktuna, Evrim Ünsal
Format:	Article
Language:	English
Published:	Galenos Publishing House 2025-10-01
Subjects:	brca1 and brca2 genes breast cancer screening breast conserving surgery parp inhibitors sequencing
Online Access:	https://www.eurjbreasthealth.com/articles/reclassification-of-lessemgreaterbrca1lessemgreater-and-lessemgreaterbrca2lessemgreater-variants-of-unknown-significance-in-a-turkish-cohort-a-single-center-retrospective-study/doi/ejbh.galenos.2025.2025-5-2