Mutational profile of oropharyngeal squamous cell carcinoma in relation to HPV, tobacco smoking and prognosis with validation in the DAHANCA 19 randomized trial

Background and purpose: This study investigated prognostic biomarkers in oropharyngeal squamous cell carcinoma (OPSCC), with a focus on tumors related to human papillomavirus (HPV) infection and potential molecular effects of tobacco smoking, as smokers with HPV+ OPSCC often have poorer outcomes. P...

Full description

Bibliographic Details

Published in:	Acta Oncologica
Main Authors:	Jacob Lilja-Fischer, Morten Horsholt Kristensen, Pernille Lassen, Torben Steiniche, Trine Tramm, Magnus Stougaard, Anders Frederiksen, Benedicte Ulhøi, Jan Alsner, Kasper Toustrup, Christian Maare, Jørgen Johansen, Hanne Primdahl, Claus Andrup Kristensen, Maria Andersen, Jesper Grau Eriksen, Jens Overgaard
Format:	Article
Language:	English
Published:	Medical Journals Sweden 2025-08-01
Subjects:	Squamous Cell Carcinoma of Head and Neck Radiotherapy Human Papillomavirus Biomarkers
Online Access:	https://medicaljournalssweden.se/actaoncologica/article/view/44042