Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease

Summary: Caspase recruitment domain family member 14 (CARD14) and its variants are associated with both atopic dermatitis (AD) and psoriasis, but their mechanistic impact on skin barrier homeostasis is largely unknown. CARD14 is known to signal via NF-κB; however, CARD14-NF-κB signaling does not ful...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Stanley B. DeVore, Matthew Schuetz, Lauren Alvey, Henry Lujan, David E. Ochayon, Lindsey Williams, Wan Chi Chang, Alyssa Filuta, Brandy Ruff, Arjun Kothari, Jennifer M. Hahn, Eric Brandt, Latha Satish, Krishna Roskin, Andrew B. Herr, Jocelyn M. Biagini, Lisa J. Martin, Deniz Cagdas, Sevgi Keles, Joshua D. Milner, Dorothy M. Supp, Gurjit K. Khurana Hershey
Format:	Article
Language:	English
Published:	Elsevier 2024-08-01
Subjects:	CP: Developmental biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124724009185