PADI4-mediated citrullination of histone H3 stimulates HIV-1 transcription

Abstract HIV-1 infection establishes a reservoir of long-lived cells with integrated proviral DNA that can persist despite antiretroviral therapy (ART). Certain reservoir cells can be reactivated to reinitiate infection. The mechanisms governing proviral latency and transcriptional regulation of the...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Luca Love, Bianca B. Jütte, Birgitta Lindqvist, Hannah Rohdjess, Oscar Kieri, Piotr Nowak, J. Peter Svensson
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-06-01
Online Access:	https://doi.org/10.1038/s41467-025-61029-0