Fidgetin interacting with microtubule end binding protein EB3 affects axonal regrowth in spinal cord injury

[INLINE:1] Fidgetin, a microtubule-severing enzyme, regulates neurite outgrowth, axonal regeneration, and cell migration by trimming off the labile domain of microtubule polymers. Because maintenance of the microtubule labile domain is essential for axon initiation, elongation, and navigation, it is...

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Bibliographic Details

Published in:	Neural Regeneration Research
Main Authors:	Chao Ma, Junpei Wang, Qifeng Tu, Weijuan Bo, Zunlu Hu, Run Zhuo, Ronghua Wu, Zhangji Dong, Liang Qiang, Yan Liu, Mei Liu
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2023-01-01
Subjects:	acetylated microtubules; axon regeneration; axonal branching; axonal regrowth; end binding protein 3; fidgetin; microtubule dynamics; sciatic nerve injury; spinal cord injury; tyrosinated microtubules
Online Access:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=12;spage=2727;epage=2732;aulast=Ma