Redirection of epithelial immune responses by short chain fatty acids through inhibition of histone deacetylases

Short-Chain Fatty Acids (SCFAs) are products of microbial fermentation that are important for intestinal epithelial health. Here we describe that SCFAs have rapid and reversible effects on Toll-like receptor (TLR) responses in epithelial cells. Incubation of HEK293 or HeLa epithelial cells with the...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Frontiers in Immunology
المؤلفون الرئيسيون:	May Young eLin, Marcel Robert de Zoete, Jos P.M. van Putten, Karin eStrijbis
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2015-11-01
الموضوعات:	Flagellin Toll-Like Receptors NF-κB histone acetylation Butyrate HDAC
الوصول للمادة أونلاين:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00554/full