Development and characterization of a unique anti‐IgE mouse monoclonal antibody cross‐reactive between human and canine IgE

Abstract Background The efficacy assessment of human anti‐IgE monoclonal antibodies (mAbs) in animal models before clinical trials is hampered due to the lack of cross‐reactivity of anti‐IgE mAbs between species. Objective We developed CRE‐DR (an anti‐dog IgE monoclonal antibody), an anti‐IgE mouse...

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Bibliographic Details

Published in:	Immunity, Inflammation and Disease
Main Authors:	Akiko Kumagai, Takuya Nara, Mizuho Uematsu, Yoko Kakinuma, Takashi Saito, Kenichi Masuda
Format:	Article
Language:	English
Published:	Wiley 2021-12-01
Subjects:	animals epitopes humans IgE | monoclonal antibody
Online Access:	https://doi.org/10.1002/iid3.531