Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the <i>Sod1</i> Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disease arising from the combined degeneration of upper motor neurons (UMN) in the motor cortex, and lower motor neurons (LMN) in the brainstem and spinal cord. This dual impairment raises two major questions: (i) are t...

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書誌詳細

出版年:	Brain Sciences
主要な著者:	Christine Marques, Thibaut Burg, Jelena Scekic-Zahirovic, Mathieu Fischer, Caroline Rouaux
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2021-03-01
主題:	amyotrophic lateral sclerosis motor cortex upper motor neurons lower motor neurons somatotopy descending propagation
オンライン･アクセス:	https://www.mdpi.com/2076-3425/11/3/369