FYN, SARS-CoV-2, and IFITM3 in the neurobiology of Alzheimer's disease
Introduction: (IFITM3) is an innate immune protein that has been identified as a novel γ-secretase (γs) modulator. FYN is a kinase that stabilizes IFITM3 on the membrane, primes APP for amyloidogenic γs processing and mediates tau oligomerization. The purpose of this study is to explore the role of...
| Published in: | Brain Disorders |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-09-01
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| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666459321000214 |